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Structure of 70724-74-2
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N-Methyl-N-(piperidin-4-yl)methanesulfonamide features a piperidine ring bearing a methanesulfonamide group and a methyl substituent, delivering enhanced solubility and metabolic stability. This scaffold integrates readily into medicinal chemistry campaigns targeting kinase inhibition and CNS-penetrant molecules, offering favorable pharmacokinetic properties under standard bench conditions.
N-Methyl-N-(piperidin-4-yl)methanesulfonamide serves as a versatile sulfonamide building block in medicinal chemistry, enabling efficient access to bioactive heterocycles. Its piperidine core offers favorable solubility and metabolic stability, while the methanesulfonyl group provides a robust handle for further functionalization. The compound exhibits bench stability and compatibility with standard coupling and reductive amination protocols, facilitating rapid scaffold diversification in lead optimization campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: