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CS-W001157 4
Total: USD 88.00

1-(tert-butoxycarbonyl)-1,2,3,6-tetrahydropyridine-4-carboxylic acid

  • CAS No. 70684-84-3

  • Cat. No. CS-W001621
  • Purity≥97%
  • MDL No.MFCD02682417

*For research and further manufacturing use only, not for direct human use.

1-(tert-butoxycarbonyl)-1,2,3,6-tetrahydropyridine-4-carboxylic acid|CS-W001621

Structure of 70684-84-3

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General Information

  • CAS No. 70684-84-3
  • Cat. No. CS-W001621
  • Purity ≥97%
  • MDL No. MFCD02682417
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₇NO₄
  • Molecular Weight 227.26
  • Synonym(s) 1-Boc-1,2,3,6-tetrahydropyridine-4-carboxylic Acid
  • SMILES O=C(N1CCC(=CC1)C(=O)O)OC(C)(C)C

Description

This tetrahydropyridine derivative features a tert-butyl carbamate-protected amine and a carboxylic acid group, enabling direct incorporation into peptide backbones or as a building block in heterocyclic synthesis. The protected nitrogen enhances stability during reaction sequences, while the electron-deficient ring facilitates selective functionalization.

Application

1-(tert-Butoxycarbonyl)-1,2,3,6-tetrahydropyridine-4-carboxylic acid serves as a versatile building block for heterocyclic synthesis, enabling efficient access to substituted pyridine and piperidine scaffolds. Its bench-stable tert-butyl ester and carboxylic acid functionalities offer orthogonal reactivity, facilitating selective derivatization and coupling reactions. Functions as a key intermediate in the construction of bioactive molecules through standard peptide coupling, hydrogenation, and functional group interconversions.

Safety Information

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GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301
Precautionary Statements : P264-P270-P405-P501

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Computational Chemistry Data

  • TPSA   66.84
  • LogP   1.6382
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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