2-(Difluoromethyl)-1H-benzo[d]imidazole

Name: 2-(Difluoromethyl)-1H-benzo[d]imidazole
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 705-09-9
Cat. No. CS-B0299
Purity≥98%
MDL No.MFCD00463015

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-(Difluoromethyl)-1H-benzo[d]imidazole|CS-B0299

Structure of 705-09-9

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 705-09-9
Cat. No. CS-B0299
Purity ≥98%
MDL No. MFCD00463015
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₆F₂N₂
Molecular Weight 168.14
Synonym(s) 2-Difluoromethyl-1H-benzoimidazole
SMILES FC(F)C1=NC2=CC=CC=C2N1

Description

2-(Difluoromethyl)-1H-benzo[d]imidazole integrates a difluoromethyl group at the 2-position of a benzimidazole core, delivering enhanced metabolic stability and lipophilicity. This electron-deficient moiety facilitates targeted interactions in medicinal chemistry applications, particularly in kinase inhibitor design and bioactive heterocycle scaffolding.

Application

2-(Difluoromethyl)-1H-benzo[d]imidazole serves as a versatile heterocyclic building block in medicinal chemistry, enabling the incorporation of a difluoromethyl group—a bioisostere of hydroxyl and methyl groups—into drug candidates. Its bench-stable nature and compatibility with standard coupling reactions facilitate efficient synthesis of fluorinated pharmaceutical scaffolds. The molecule functions as a key intermediate in the development of kinase inhibitors and CNS-targeted therapeutics, offering enhanced metabolic stability and membrane permeability.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 28.68
LogP 2.5005
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Benzimidazole compounds

Key Words

2-(Difluoromethyl)-1H-benzo[d]imidazole sigma2-(Difluoromethyl)-1H-benzo[d]imidazole manufacturer2-(Difluoromethyl)-1H-benzo[d]imidazole price2-(Difluoromethyl)-1H-benzo[d]imidazole structure2-(Difluoromethyl)-1H-benzo[d]imidazole SDSbuy 2-(Difluoromethyl)-1H-benzo[d]imidazole2-(Difluoromethyl)-1H-benzo[d]imidazole supplier2-(Difluoromethyl)-1H-benzo[d]imidazole uses2-(Difluoromethyl)-1H-benzo[d]imidazole molecular weightprice of 2-(Difluoromethyl)-1H-benzo[d]imidazole2-(Difluoromethyl)-1H-benzo[d]imidazole chemical name formula of 2-(Difluoromethyl)-1H-benzo[d]imidazole

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-(Difluoromethyl)-1H-benzo[d]imidazole

CAS No. 705-09-9

Recommended Products