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Structure of 704-41-6
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1-Ethynyl-2-(trifluoromethyl)benzene features a terminal alkyne group conjugated to an electron-deficient trifluoromethyl-substituted phenyl ring. This combination enhances reactivity in copper-catalyzed coupling processes while maintaining bench-stable handling properties. The molecule integrates readily into complex scaffolds via click chemistry and serves as a key building block for bioactive molecules and functional materials.
1-Ethynyl-2-(trifluoromethyl)benzene serves as a versatile building block in transition-metal-catalyzed coupling reactions, enabling efficient access to conjugated arylalkynes. Its trifluoromethyl group enhances metabolic stability and modulates electronic properties, while the terminal alkyne facilitates Sonogashira, Glaser, and click-type transformations. The compound exhibits excellent bench stability and compatibility with diverse functional groups, making it ideal for constructing complex scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS02
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Signal Word : Warning
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UN#: 1993
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Class : 3
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Packing Group : Ⅲ
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Hazard Statements : H226
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P501
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Lot numbers can be found on the outside label of a product: