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Structure of 7033-39-8
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5-Bromo-1,3-dimethylpyrimidine-2,4(1H,3H)-dione features a brominated pyrimidinedione core with methyl substituents at the 1- and 3-positions, delivering enhanced electrophilicity at C5. This structure enables efficient coupling in cross-coupling reactions and serves as a key scaffold in medicinal chemistry. The compound exhibits bench-stable handling and compatibility with standard synthetic protocols.
5-Bromo-1,3-dimethylpyrimidine-2,4(1H,3H)-dione serves as a versatile building block in heterocyclic synthesis, enabling efficient access to pyrimidine-based scaffolds. Its bromine substituent facilitates palladium-catalyzed cross-coupling reactions, while the dimethylated diketone core provides orthogonal reactivity for further functionalization. The compound exhibits excellent bench stability and is readily purified by recrystallization, making it well-suited for iterative medicinal chemistry campaigns and process-scale applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501
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Lot numbers can be found on the outside label of a product: