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CS-W001157 4
Total: USD 88.00

2-(2-(Phenylamino)phenyl)acetic acid

  • CAS No. 70172-33-7

  • Cat. No. CS-W013007
  • Purity≥98%
  • MDL No.MFCD03265448

*For research and further manufacturing use only, not for direct human use.

2-(2-(Phenylamino)phenyl)acetic acid|CS-W013007

Structure of 70172-33-7

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General Information

  • CAS No. 70172-33-7
  • Cat. No. CS-W013007
  • Purity ≥98%
  • MDL No. MFCD03265448
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₃NO₂
  • Molecular Weight 227.26
  • Synonym(s) 2-Anilinophenylacetic acid
  • SMILES O=C(O)CC1=CC=CC=C1NC2=CC=CC=C2

Description

This phenylamino-substituted acetic acid derivative features a rigid ortho-aminobiphenyl scaffold that enhances π-conjugation and facilitates coordination in metal complexes. Its amine-functionalized aryl group enables direct coupling in peptide synthesis and supports conjugation to biomolecules via amide bond formation. The molecule exhibits favorable solubility in organic solvents and stability under standard bench conditions.

Application

2-(2-(Phenylamino)phenyl)acetic acid serves as a versatile scaffold for constructing biologically relevant heterocycles and functionalized aromatic systems. Its ortho-aminobenzyl carboxylic acid motif enables efficient cyclization reactions, facilitates metal-catalyzed coupling processes, and offers compatibility with common protecting group strategies. The molecule exhibits good bench stability and ease of purification, making it a practical building block in medicinal chemistry and process development workflows.

Synthesis

  • Route1

    References

    • Shindikar; Khan; Viswanathan European Journal of Medicinal Chemistry, 2006 , vol. 41, # 6 p. 786 - 792
  • Route2

    References

    • Monguchi, Yasunari; Kume, Akira; Hattori, Kazuyuki; Maegawa, Tomohiro; Sajiki, Hironao Tetrahedron, 2006 , vol. 62, # 33 p. 7926 - 7933
  • Route3
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    • ~%
    • In-stock
      2-(2-(Phenylamino)phenyl)acetic acid|CS-W013007
      70172-33-7

    References

    • European Journal of Medicinal Chemistry, , vol. 41, # 6 p. 786 - 792

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   49.33
  • LogP   3.0573
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   4

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