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CS-W001157 4
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2-(2'-Bromophenoxy)propane

  • CAS No. 701-07-5

  • Cat. No. CS-W014904
  • Molecule weight215.09
  • Purity≥98%
  • MDL No.MFCD00070759

*For research and further manufacturing use only, not for direct human use.

2-(2'-Bromophenoxy)propane|CS-W014904

Structure of 701-07-5

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General Information

  • CAS No. 701-07-5
  • Cat. No. CS-W014904
  • Purity ≥98%
  • MDL No. MFCD00070759
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁BrO
  • Molecular Weight 215.09
  • Synonym(s) 2-(2-Bromophenoxy)propane
  • SMILES CC(C)OC1=CC=CC=C1Br

Description

2-(2'-Bromophenoxy)propane features a brominated aromatic ring linked via an ether bond to a propanol backbone, delivering enhanced reactivity in electrophilic substitution and coupling processes. This structure enables efficient integration into pharmaceutical intermediates and agrochemical scaffolds under standard conditions.

Application

2-(2'-Bromophenoxy)propane serves as a versatile building block in synthetic organic chemistry, enabling efficient construction of aryl ether linkages under palladium-catalyzed coupling conditions. Its brominated aromatic ring facilitates cross-coupling reactions with boronic acids and nucleophiles, while the propanol moiety offers potential for further functionalization. The compound exhibits good bench stability and is readily purified by standard chromatographic methods, making it suitable for use in medicinal chemistry campaigns and process development workflows.

Synthesis

  • Route1
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      95-56-7
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      75-26-3
    • ~95%
    • In-stock
      2-(2'-Bromophenoxy)propane|CS-W014904
      701-07-5

    References

    • Ishikawa; Shimooka; Narioka; Noguchi; Saito; Yamazaki; Harayama; Seki; Yamaguchi Journal of Organic Chemistry, 2000 , vol. 65, # 26 p. 9143 - 9151
  • Route2
    • null|null
      75-30-9
    • null|null
      95-56-7
    • ~%
    • In-stock
      2-(2'-Bromophenoxy)propane|CS-W014904
      701-07-5

    References

    • US6004959 A1, ; US 6004959 A
  • Route3
    • null|null
      95-56-7
    • ~%
    • In-stock
      2-(2'-Bromophenoxy)propane|CS-W014904
      701-07-5

    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 14 p. 3930 - 3934

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   9.23
  • LogP   3.2363
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   2

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