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CS-W001157 4
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3-Fluoro-5-methoxybenzaldehyde

  • CAS No. 699016-24-5

  • Cat. No. CS-W008289
  • Purity≥97%
  • MDL No.MFCD08741376

*For research and further manufacturing use only, not for direct human use.

3-Fluoro-5-methoxybenzaldehyde|CS-W008289

Structure of 699016-24-5

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General Information

  • CAS No. 699016-24-5
  • Cat. No. CS-W008289
  • Purity ≥97%
  • MDL No. MFCD08741376
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇FO₂
  • Molecular Weight 154.14
  • Synonym(s) Benzaldehyde, 3-fluoro-5-methoxy- (9CI)
  • SMILES FC1=CC(=CC(=C1)C=O)OC

Description

3-Fluoro-5-methoxybenzaldehyde is a fluorinated aromatic aldehyde featuring electron-donating methoxy and electron-withdrawing fluoro substituents in a meta-para relationship. This electronic asymmetry enhances reactivity in nucleophilic additions and facilitates selective functionalization. The compound exhibits good stability under standard conditions and integrates readily into synthetic sequences for pharmaceutical intermediates and advanced materials.

Application

3-Fluoro-5-methoxybenzaldehyde serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling the construction of bioactive heterocycles and functionalized aromatic scaffolds. Its electron-withdrawing fluorine and electron-donating methoxy groups provide orthogonal reactivity for selective transformations. The aldehyde functionality facilitates imine formation, reductive amination, and coupling reactions, while the compound exhibits excellent bench stability and ease of purification.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   1.6468
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   2

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