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CS-W001157 4
Total: USD 88.00

Bis(tri-o-tolylphosphine)palladium(0)

  • CAS No. 69861-71-8

  • Cat. No. CS-W008278
  • Purity≥98%
  • MDL No.MFCD12911908

*For research and further manufacturing use only, not for direct human use.

Bis(tri-o-tolylphosphine)palladium(0)|CS-W008278

Structure of 69861-71-8

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General Information

  • CAS No. 69861-71-8
  • Cat. No. CS-W008278
  • Purity ≥98%
  • MDL No. MFCD12911908
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄₂H₄₂P₂Pd
  • Molecular Weight 715.15
  • Synonym(s) None
  • SMILES CC1=CC=CC=C1[P](C2=CC=CC=C2C)([Pd][P](C3=CC=CC=C3C)(C4=CC=CC=C4C)C5=CC=CC=C5C)C6=CC=CC=C6C

Application

Bis(tri-o-tolylphosphine)palladium(0) serves as a highly effective, bench-stable catalyst for cross-coupling reactions, enabling efficient C–C and C–heteroatom bond formation under mild conditions. Its sterically shielded tri-o-tolylphosphine ligands enhance stability and reactivity in Suzuki-Miyaura, Stille, and Negishi couplings, offering excellent functional group tolerance and ease of purification. This catalyst is particularly valuable in complex molecule synthesis where reproducibility and operational simplicity are critical.

Synthesis

  • Route1
    • null|null
      52409-22-0
    • Tri(2-methylphenyl)phosphine Eletriptan Impurity|CS-0229714
      6163-58-2
    • ~69%
    • In-stock
      Bis(tri-o-tolylphosphine)palladium(0)|CS-W008278
      69861-71-8

    References

    • Harding, Brennen A.; Melvin, Patrick R.; Dougherty, William; Kassel, Scott; Goodson, Felix E. Organometallics, 2013 , vol. 32, # 12 p. 3570 - 3573
  • Route2
    • null|null
      210691-06-8
    • ~10%
    • In-stock
      Bis(tri-o-tolylphosphine)palladium(0)|CS-W008278
      69861-71-8
    • null|null
      252008-03-0

    References

    • Krause, Jochen; Cestaric, Guenter; Haack, Karl-Josef; Seevogel, Klaus; Storm, Werner; Poerschke, Klaus-Richard Journal of the American Chemical Society, 1999 , vol. 121, # 42 p. 9807 - 9823
  • Route3
    • Tri(2-methylphenyl)phosphine Eletriptan Impurity|CS-0229714
      6163-58-2
    • Bis(dibenzylideneacetone)palladium, High quality|CS-1383709
      32005-36-0
    • ~%
    • In-stock
      Bis(tri-o-tolylphosphine)palladium(0)|CS-W008278
      69861-71-8

    References

    • Paul, Frederic; Patt, Joe; Hartwig, John F. Journal of the American Chemical Society, 1994 , vol. 116, # 13 p. 5969 - 5970

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02
Signal Word : Danger
UN#: 1325
Class : 4.1
Packing Group : Ⅱ
Hazard Statements : H228
Precautionary Statements : P210-P240-P241-P280-P370+P378

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   8.20222
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   8

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