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(4S,4'S)-2,2'-(1-Phenylpropane-2,2-diyl)bis(4-isopropyl-4,5-dihydrooxazole)

  • CAS No. 698350-53-7

  • Cat. No. CS-0145098
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(4S,4'S)-2,2'-(1-Phenylpropane-2,2-diyl)bis(4-isopropyl-4,5-dihydrooxazole)|CS-0145098

Structure of 698350-53-7

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General Information

  • CAS No. 698350-53-7
  • Cat. No. CS-0145098
  • Purity ≥95%
  • MDL No. None
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₁H₃₀N₂O₂
  • Molecular Weight None
  • Synonym(s) None
  • SMILES CC(C)[C@@H]1N=C(C(C)(CC2=CC=CC=C2)C3=N[C@@H](C(C)C)CO3)OC1

Description

This chiral bisoxazole features a rigid 1-phenylpropane-2,2-diyl linker enabling precise spatial orientation of two electron-rich dihydrooxazole rings. Designed for asymmetric synthesis, the molecule integrates sterically hindered isopropyl groups that enhance conformational stability and reduce side reactivity. Its bench-stable nature supports reliable use in catalytic systems and ligand development.

Application

(4S,4'S)-2,2'-(1-Phenylpropane-2,2-diyl)bis(4-isopropyl-4,5-dihydrooxazole) serves as a chiral bis-oxazoline ligand enabling efficient asymmetric catalysis in transition-metal-mediated transformations. Its rigid, C₂-symmetric architecture and isopropyl-substituted oxazole rings provide excellent stereocontrol and functional group tolerance. The molecule exhibits bench stability, facilitates straightforward purification, and functions reliably in standard synthetic workflows for enantioselective synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   43.18
  • LogP   4.142
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   6

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