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CS-W001157 4
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4-(Methylamino)butanoic acid hydrochloride

  • CAS No. 6976-17-6

  • Cat. No. CS-0096860
  • Purity≥95%
  • MDL No.MFCD00012612

*For research and further manufacturing use only, not for direct human use.

4-(Methylamino)butanoic acid hydrochloride|CS-0096860

Structure of 6976-17-6

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General Information

  • CAS No. 6976-17-6
  • Cat. No. CS-0096860
  • Purity ≥95%
  • MDL No. MFCD00012612
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₂ClNO₂
  • Molecular Weight 153.61
  • Synonym(s) 4-(Methylamino)butyric acid hydrochloride
  • SMILES O=C(O)CCCNC.[H]Cl

Description

4-(Methylamino)butanoic acid hydrochloride is a bench-stable, moisture-tolerant amino acid derivative featuring a primary amine and carboxylic acid functional group separated by a four-carbon chain. This zwitterionic salt integrates readily into peptide synthesis workflows, offering enhanced solubility in aqueous and polar organic media. The methylamino substituent provides tunable basicity and facilitates downstream conjugation reactions.

Application

4-(Methylamino)butanoic acid hydrochloride serves as a valuable building block for bioactive amine-containing heterocycles and peptide derivatives. Its zwitterionic character enhances solubility and stability in aqueous media, while the pendant primary amine enables straightforward functionalization via acylation, alkylation, or coupling reactions. The compound demonstrates excellent bench stability and compatibility with standard purification techniques, facilitating efficient incorporation into complex molecular architectures relevant to medicinal chemistry and process development workflows.

Synthesis

  • Route1

    References

    • Synthesis, , # 6 p. 468 - 469

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   49.33
  • LogP   0.4924
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   4

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