7-Chlorothieno[3,2-b]pyridine

Name: 7-Chlorothieno[3,2-b]pyridine
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CAS No. 69627-03-8
Cat. No. CS-D0325
Purity≥95%
MDL No.MFCD08448161

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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Structure of 69627-03-8

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General Information

CAS No. 69627-03-8
Cat. No. CS-D0325
Purity ≥95%
MDL No. MFCD08448161
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₄ClNS
Molecular Weight 169.63
Synonym(s) 7-Chlorthieno[3,2-b]pyridin
SMILES ClC1=C2C(C=CS2)=NC=C1

Description

7-Chlorothieno[3,2-b]pyridine features a fused thienopyridine core with a chlorine substituent at the 7-position, conferring enhanced electron-deficiency and stability. This scaffold integrates readily into pharmaceutical intermediates and functional materials, offering predictable reactivity in cross-coupling and electrophilic substitution processes under standard conditions.

Application

7-Chlorothieno[3,2-b]pyridine serves as a versatile heterocyclic building block for medicinal chemistry and materials science applications. Its electron-deficient thienopyridine core enables efficient coupling reactions and facilitates functionalization at multiple positions. The chloro substituent provides a reliable handle for palladium-catalyzed cross-coupling transformations, enhancing synthetic accessibility in the development of bioactive compounds and advanced organic semiconductors.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 12.89
LogP 2.9497
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 0

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Aromatic heterocycle compounds Thiophene compounds

Key Words

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7-Chlorothieno[3,2-b]pyridine

CAS No. 69627-03-8

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