N-(9-((2R,3R,4R,5R)-3-((tert-Butyldimethylsilyl)oxy)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide

Name: N-(9-((2R,3R,4R,5R)-3-((tert-Butyldimethylsilyl)oxy)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 69504-07-0
Cat. No. CS-0542307
Purity≥98%
MDL No.MFCD28134644

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

N-(9-((2R,3R,4R,5R)-3-((tert-Butyldimethylsilyl)oxy)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide|CS-0542307

Structure of 69504-07-0

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 69504-07-0
Cat. No. CS-0542307
Purity ≥98%
MDL No. MFCD28134644
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₃H₃₁N₅O₅Si
Molecular Weight 485.61
Synonym(s) N6-benzoyl-2'-O-(tert-butyldiMethylsilyl)adenosine
SMILES CC(C)(C)[Si](C)(C)O[C@H]1[C@@](N2C3=NC=NC(NC(C4=CC=CC=C4)=O)=C3N=C2)([H])O[C@@H]([C@H]1O)CO

Description

This N-(9-((2R,3R,4R,5R)-3-((tert-Butyldimethylsilyl)oxy)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide features a protected ribose mimic with orthogonal functional handles, enabling seamless incorporation into nucleoside analogs. The tert-butyldimethylsilyl group ensures stability during synthesis, while the benzamide moiety provides a robust anchor for conjugation and purification workflows under standard conditions.

Application

N-(9-((2R,3R,4R,5R)-3-((tert-Butyldimethylsilyl)oxy)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide serves as a key nucleoside analog intermediate, enabling efficient synthesis of purine-based building blocks. The protected hydroxyl groups provide exceptional bench stability and orthogonal reactivity, facilitating selective deprotection and functionalization in complex molecule assembly. Its compatibility with standard coupling protocols and robust handling make it ideal for medicinal chemistry campaigns requiring precise glycosylation control.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 131.62
LogP 2.7196
H_Acceptors 9
H_Donors 3
Rotatable_Bonds 6

Other Classifications

Building Blocks Functional Group Organosilicon compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Aromatic heterocycle compounds Purine compounds

Catalysis Compounds by Element Classes Metal Compounds Semimetal Compounds

Biochemistry Biochemicals and Reagents Nucleosides, Nucleotides, Oligonucleotides Nucleobases and their Analogs

Biochemistry Biochemicals and Reagents Nucleosides, Nucleotides, Oligonucleotides Nucleoside Analogs

Biochemistry Biochemicals and Reagents Nucleosides, Nucleotides, Oligonucleotides Nucleosides

Key Words

69504-07-0 sigma69504-07-0 manufacturer69504-07-0 price69504-07-0 structure69504-07-0 SDSbuy 69504-07-069504-07-0 supplier69504-07-0 uses69504-07-0 molecular weightprice of 69504-07-069504-07-0 chemical name formula of 69504-07-0

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

N-(9-((2R,3R,4R,5R)-3-((tert-Butyldimethylsilyl)oxy)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide

CAS No. 69504-07-0

Recommended Products