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Structure of 6946-15-2
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This hydroxy-methyl-nitrobenzoic acid features a strategically positioned para-nitro group and a vicinal hydroxyl moiety, enabling efficient coupling in synthetic routes. The carboxylic acid functionality facilitates derivatization, while the electron-withdrawing nitro group enhances reactivity in electrophilic substitution processes.
3-Hydroxy-4-methyl-2-nitrobenzoic acid serves as a versatile building block for nitro-aromatic synthesis, enabling direct functionalization at the benzylic position and facilitating subsequent transformations such as reduction to amino derivatives or cyclization to heterocyclic scaffolds. Its ortho-hydroxyl and meta-methyl groups provide complementary reactivity for selective derivatization, while the carboxylic acid functionality supports straightforward coupling and salt formation. The compound exhibits sufficient bench stability for routine handling and purification via recrystallization or chromatography.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: