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CS-W001157 4
Total: USD 88.00

3-Hydroxy-4-methyl-2-nitrobenzoic acid

  • CAS No. 6946-15-2

  • Cat. No. CS-0100666
  • Purity≥98%
  • MDL No.MFCD00007106
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3-Hydroxy-4-methyl-2-nitrobenzoic acid|CS-0100666

Structure of 6946-15-2

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Description

This hydroxy-methyl-nitrobenzoic acid features a strategically positioned para-nitro group and a vicinal hydroxyl moiety, enabling efficient coupling in synthetic routes. The carboxylic acid functionality facilitates derivatization, while the electron-withdrawing nitro group enhances reactivity in electrophilic substitution processes.

Application

3-Hydroxy-4-methyl-2-nitrobenzoic acid serves as a versatile building block for nitro-aromatic synthesis, enabling direct functionalization at the benzylic position and facilitating subsequent transformations such as reduction to amino derivatives or cyclization to heterocyclic scaffolds. Its ortho-hydroxyl and meta-methyl groups provide complementary reactivity for selective derivatization, while the carboxylic acid functionality supports straightforward coupling and salt formation. The compound exhibits sufficient bench stability for routine handling and purification via recrystallization or chromatography.

General Information

  • CAS No. 6946-15-2
  • Cat. No. CS-0100666
  • Purity ≥98%
  • MDL No. MFCD00007106
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇NO₅
  • Molecular Weight 197.14
  • Synonym(s) copper 2,3,4,5,6,7-hexahydroxyheptanoate
  • SMILES O=C(O)C1=CC=C(C)C(O)=C1[N+]([O-])=O

Computational Chemistry Data

  • TPSA   100.67
  • LogP   1.30702
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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