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Structure of 6945-92-2
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Ethyl hydrazinoacetate hydrochloride has been used in the preparation of three novel copper(II) complexes as condensation derivatives of 2-pyridinecarboxaldehyde, 2-acetylpyridine and 2-quinolinecarboxaldehyde.
Ethyl 2-hydrazinylacetate hydrochloride serves as a versatile building block for heterocyclic synthesis, enabling efficient access to pyrazole and triazole scaffolds under mild conditions. Its hydrazinyl group exhibits high reactivity toward carbonyl compounds and activated alkenes, facilitating one-pot cyclizations with excellent functional group tolerance. The hydrochloride salt enhances bench stability and simplifies handling, while the ethyl ester moiety supports downstream derivatization via hydrolysis or nucleophilic substitution. This compound is particularly valuable in medicinal chemistry workflows requiring rapid scaffold diversification.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: