Methyl 5-amino-2-bromobenzoate

Name: Methyl 5-amino-2-bromobenzoate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 6942-37-6
Cat. No. CS-W005932
Purity≥95%
MDL No.MFCD00085568

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Methyl 5-amino-2-bromobenzoate|CS-W005932

Structure of 6942-37-6

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 6942-37-6
Cat. No. CS-W005932
Purity ≥95%
MDL No. MFCD00085568
Storage RT, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₈BrNO₂
Molecular Weight 230.06
Synonym(s) Benzoic acid, 5-amino-2-bromo-, methyl ester
SMILES O=C(OC)C1=CC(N)=CC=C1Br

Description

Methyl 5-amino-2-bromobenzoate features a bromine atom at the ortho position relative to the ester group and an amino substituent at the para position, creating a versatile scaffold for synthetic modifications. This electron-rich aromatic system enables efficient coupling reactions under mild conditions. The molecule exhibits enhanced solubility in common organic solvents and maintains stability during standard bench handling, facilitating its use in pharmaceutical intermediates and agrochemical synthesis.

Application

Methyl 5-amino-2-bromobenzoate serves as a versatile building block in medicinal chemistry, enabling sequential functionalization via the orthogonal reactivity of its amino and bromo groups. The amino group facilitates coupling reactions, while the bromo moiety supports palladium-catalyzed cross-couplings, allowing efficient access to substituted biaryls and complex heterocycles. Bench-stable and amenable to standard purification methods, it functions effectively in multi-step syntheses requiring precise regiocontrol.

Synthesis

Route1
- In-stock
  
  6942-36-5
- ~99%
- In-stock
  
  6942-37-6
References
- Chin, Elbert; Li, Jim; Lui, Albert Sui-Ting; Talamas, Francisco Xavier Patent: US2010/297073 A1, 2010 ; Location in patent: Page/Page column 20 ;
Route2
- 67-56-1
- 22921-67-1
- ~%
- In-stock
  
  6942-37-6
References
- WO2007/99200 A1, ; Page/Page column 9-10 ; WO 2007/099200 A1
Route3
- In-stock
  
  4518-10-9
- ~82%
- In-stock
  
  6942-37-6
- In-stock
  
  106896-48-4
References
- Synthesis, , # 8 art. no. P12608SS, p. 1305 - 1308

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS06
Signal Word : Danger	UN#: 2811
Class : 6.1	Packing Group : Ⅲ
Hazard Statements : H301
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 52.32
LogP 1.8179
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Functional Group Ester

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

Methyl 5-amino-2-bromobenzoate sigmaMethyl 5-amino-2-bromobenzoate manufacturerMethyl 5-amino-2-bromobenzoate priceMethyl 5-amino-2-bromobenzoate structureMethyl 5-amino-2-bromobenzoate SDSbuy Methyl 5-amino-2-bromobenzoateMethyl 5-amino-2-bromobenzoate supplierMethyl 5-amino-2-bromobenzoate usesMethyl 5-amino-2-bromobenzoate molecular weightprice of Methyl 5-amino-2-bromobenzoateMethyl 5-amino-2-bromobenzoate chemical name formula of Methyl 5-amino-2-bromobenzoate

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Methyl 5-amino-2-bromobenzoate

CAS No. 6942-37-6

Recommended Products

General Information

Description

Application

Synthesis

References

References

References

Safety Information

Quality Control

Computational Chemistry Data

Similar Products

Other Classifications

Recently Viewed Products

Key Words