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CS-W001157 4
Total: USD 88.00

5-Amino-4,6-dihydroxypyrimidine

  • CAS No. 69340-97-2

  • Cat. No. CS-0188409
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-Amino-4,6-dihydroxypyrimidine|CS-0188409

Structure of 69340-97-2

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General Information

  • CAS No. 69340-97-2
  • Cat. No. CS-0188409
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₅N₃O₂
  • Molecular Weight 127.10
  • Synonym(s) 4,6-Dihydroxy-5-amino-pyrimidin
  • SMILES C1=NC(=C(C(=N1)O)N)O

Description

5-Amino-4,6-dihydroxypyrimidine is a trihydroxypyrimidine derivative featuring complementary functional groups for bioconjugation and molecular scaffold development. This bench-stable compound integrates readily into nucleoside analogs and heterocyclic architectures, offering enhanced solubility and reactivity under standard conditions.

Application

5-Amino-4,6-dihydroxypyrimidine serves as a versatile building block in heterocyclic synthesis, enabling efficient access to pyrimidine-based scaffolds through orthogonal functionalization. Its amino and hydroxyl groups facilitate regioselective derivatization, including amidation, etherification, and metal-catalyzed coupling reactions. The compound exhibits good bench stability and is readily purified by recrystallization, making it well-suited for medicinal chemistry campaigns and API intermediate development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   92.26
  • LogP   -0.53
  • H_Acceptors   5
  • H_Donors   3
  • Rotatable_Bonds   0

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