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CS-W001157 4
Total: USD 88.00

4-(Dimethylamino)butanoic acid

  • CAS No. 693-11-8

  • Cat. No. CS-0117583
  • Purity≥95%
  • MDL No.MFCD00044628

*For research and further manufacturing use only, not for direct human use.

4-(Dimethylamino)butanoic acid|CS-0117583

Structure of 693-11-8

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General Information

  • CAS No. 693-11-8
  • Cat. No. CS-0117583
  • Purity ≥95%
  • MDL No. MFCD00044628
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₃NO₂
  • Molecular Weight 131.17
  • Synonym(s) N,N-Dimethyl-g-aminobutyric acid
  • SMILES O=C(O)CCCN(C)C

Description

4-(Dimethylamino)butanoic acid features a polar amine group flanked by a flexible alkyl chain, enabling solubility in aqueous and organic media. This structure supports integration into peptide conjugates and bioactive scaffolds, where the basic nitrogen enhances cell permeability and facilitates protonation under physiological conditions.

Application

4-(Dimethylamino)butanoic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive amine-containing compounds through standard peptide coupling and functional group transformations. Its aliphatic amine functionality offers favorable solubility and reactivity profile, facilitating incorporation into heterocyclic scaffolds and peptidomimetics. The compound exhibits good bench stability and compatibility with common purification methods, making it suitable for scalable synthesis workflows.

Synthesis

  • Route1
    • null|null
      50-00-0
    • γ-Aminobutyric acid Vigabatrin  Impurity|CS-0228792
      56-12-2
    • ~88%
    • In-stock
      4-(Dimethylamino)butanoic acid|CS-0117583
      693-11-8

    References

    • Rahal, Said; Badache, Leila Tetrahedron Letters, 1991 , vol. 32, # 31 p. 3847 - 3848
  • Route2

    References

    • Andersson, Lars; Kuehler, Thomas; Nilsson, Martin Synthesis, 1981 , # 6 p. 468 - 469
  • Route3
    • null|null
      104459-70-3
    • ~%
    • In-stock
      4-(Dimethylamino)butanoic acid|CS-0117583
      693-11-8

    References

    • Tylichova, Martina; Kopecny, David; Morera, Solange; Briozzo, Pierre; Lenobel, Rene; Snegaroff, Jacques; Sebela, Marek Journal of Molecular Biology, 2010 , vol. 396, # 4 p. 870 - 882

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   40.54
  • LogP   0.4128
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   4

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