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Bis(2,4-di-tert-butylphenyl) hydrogen phosphate

  • CAS No. 69284-93-1

  • Cat. No. CS-0161519
  • Purity≥98%
  • MDL No.MFCD29059882

*For research and further manufacturing use only, not for direct human use.

Bis(2,4-di-tert-butylphenyl) hydrogen phosphate|CS-0161519

Structure of 69284-93-1

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General Information

  • CAS No. 69284-93-1
  • Cat. No. CS-0161519
  • Purity ≥98%
  • MDL No. MFCD29059882
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₈H₄₃O₄P
  • Molecular Weight 474.61
  • Synonym(s) 2,4-BIS(1,1-DIMETHYLETHYL)PHENOL PHOSPHATE
  • SMILES O=P(OC1=CC=C(C(C)(C)C)C=C1C(C)(C)C)(OC2=CC=C(C(C)(C)C)C=C2C(C)(C)C)O

Description

Bis(2,4-di-tert-butylphenyl) hydrogen phosphate features a sterically shielded phosphorus center flanked by two bulky aryl groups, enhancing stability and resistance to hydrolysis. This bench-stable reagent facilitates selective phosphorylation reactions under mild conditions, offering robust performance in synthetic workflows requiring moisture-tolerant phosphate transfer.

Application

Bis(2,4-di-tert-butylphenyl) hydrogen phosphate serves as a robust, bench-stable phosphite reagent enabling efficient phosphorylation and protection of alcohols under mild conditions. Its sterically shielded aryl groups confer high functional group tolerance and resistance to oxidation, facilitating clean reactions with minimal side products. The compound functions effectively in the synthesis of phosphate esters and as a stabilizing agent in catalytic systems, offering reliable performance in complex synthetic sequences.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H317-H319
Precautionary Statements : P261-P272-P280-P302+P352-P305+P351+P338-P337+P313-P333+P317-P362+P364-P501

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Computational Chemistry Data

  • TPSA   55.76
  • LogP   8.4348
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   4

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