3,3-Dimethyl-1,5-dioxaspiro[5.5]undecan-9-one

Name: 3,3-Dimethyl-1,5-dioxaspiro[5.5]undecan-9-one
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 69225-59-8
Cat. No. CS-W013207
Molecule weight198.26
Purity≥95%
MDL No.MFCD00006652

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3,3-Dimethyl-1,5-dioxaspiro[5.5]undecan-9-one|CS-W013207

Structure of 69225-59-8

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 69225-59-8
Cat. No. CS-W013207
Purity ≥95%
MDL No. MFCD00006652
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₁H₁₈O₃
Molecular Weight 198.26
Synonym(s) 3,3-Dimethyl-1,5-dioxaspiro[5.5]undecan-8-one; 3,3-Dimethyl-1,5-dioxaspiro[5.5]undecan-9-one
SMILES O=C(CC1)CCC21OCC(C)(C)CO2

Description

This spirocyclic ketone features a rigid, electron-deficient dioxane ring fused to a five-membered lactone, enabling selective reactivity in synthetic transformations. Its sterically shielded carbonyl group resists nucleophilic attack under standard conditions, offering stability during multistep sequences. The dimethyl substitution enhances solubility in polar aprotic solvents while maintaining thermal robustness. This scaffold serves as a key building block for complex natural product analogs and constrained molecular architectures.

Synthesis

Route1
- 69825-15-6
- ~88%
- In-stock
  
  69225-59-8
References
- National University Corporation Nagoya University Patent: EP2085373 A1, 2009 ; Location in patent: Page/Page column 12; 14-15 ;
Route2
- 126-30-7
- In-stock
  
  637-88-7
- ~73%
- In-stock
  
  69225-59-8
References
- F. HOFFMANN-LA ROCHE AG Patent: WO2007/48717 A1, 2007 ; Location in patent: Page/Page column 23 ;
Route3
- 7778-54-3
- 69825-15-6
- ~96%
- In-stock
  
  69225-59-8
References
- Eli Lilly and Company Patent: US4587351 A1, 1986 ;

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335-H412
Precautionary Statements : P261-P264-P270-P271-P273-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 35.53
LogP 1.8988
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 0

Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Other aliphatic heterocycles compounds

Building Blocks Skeleton Spirol Rings compounds

Key Words

69225-59-8 sigma69225-59-8 manufacturer69225-59-8 price69225-59-8 structure69225-59-8 SDSbuy 69225-59-869225-59-8 supplier69225-59-8 uses69225-59-8 molecular weightprice of 69225-59-869225-59-8 chemical name formula of 69225-59-8

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

3,3-Dimethyl-1,5-dioxaspiro[5.5]undecan-9-one

CAS No. 69225-59-8

Recommended Products

General Information

Description

Synthesis

References

References

References

Safety Information

Quality Control

Computational Chemistry Data

Similar Products

Other Classifications

Recently Viewed Products

Key Words