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CS-W001157 4
Total: USD 88.00

Dimethyl 1,1-cyclopropanedicarboxylate

  • CAS No. 6914-71-2

  • Cat. No. CS-0008577
  • Purity≥98%
  • MDL No.MFCD00192079

*For research and further manufacturing use only, not for direct human use.

Dimethyl 1,1-cyclopropanedicarboxylate|CS-0008577

Structure of 6914-71-2

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General Information

  • CAS No. 6914-71-2
  • Cat. No. CS-0008577
  • Purity ≥98%
  • MDL No. MFCD00192079
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₀O₄
  • Molecular Weight 158.15
  • Synonym(s) Dimethyl cyclopropane-1,1-dicarboxylate; Dimethyl 1,1-cyclopropanedicarboxylate
  • SMILES O=C(C1(C(OC)=O)CC1)OC

Description

Dimethyl 1,1-cyclopropanedicarboxylate may be used in the preparation of -diazo--ketoester.

Application

Dimethyl 1,1-cyclopropanedicarboxylate serves as a versatile building block in synthetic organic chemistry, enabling the construction of cyclopropane-containing scaffolds via standard functional group transformations. Its dual ester functionality facilitates sequential derivatization, while the strained cyclopropane ring enhances reactivity in nucleophilic additions and cycloadditions. The compound exhibits good bench stability and is compatible with common purification methods, making it well-suited for iterative synthesis workflows in medicinal chemistry and process development.

Synthesis

  • Route1
    • null|null
      106-93-4
    • In-stock
      Dimethyl malonate|CS-0019394
      108-59-8
    • ~92%
    • In-stock
      Dimethyl 1,1-cyclopropanedicarboxylate|CS-0008577
      6914-71-2

    References

    • Tetrahedron Letters, , vol. 46, # 4 p. 635 - 638
  • Route2
    • null|null
      107-06-2
    • In-stock
      Dimethyl malonate|CS-0019394
      108-59-8
    • ~86%
    • In-stock
      Dimethyl 1,1-cyclopropanedicarboxylate|CS-0008577
      6914-71-2

    References

    • Synthesis, , # 8 p. 738 - 739
  • Route3

    References

    • Synthetic Communications, , vol. 26, # 3 p. 525 - 530

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   52.6
  • LogP   0.1126
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   2

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