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CS-W001157 4
Total: USD 88.00

4-(Hydroxymethyl)phenoxyacetic acid

  • CAS No. 68858-21-9

  • Cat. No. CS-W017129
  • Purity≥98%
  • MDL No.MFCD00057827

*For research and further manufacturing use only, not for direct human use.

4-(Hydroxymethyl)phenoxyacetic acid|CS-W017129

Structure of 68858-21-9

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General Information

  • CAS No. 68858-21-9
  • Cat. No. CS-W017129
  • Purity ≥98%
  • MDL No. MFCD00057827
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀O₄
  • Molecular Weight 182.18
  • Synonym(s) None
  • SMILES O=C(O)COC1=CC=C(CO)C=C1

Description

4-(Hydroxymethyl)phenoxyacetic acid features a phenolic ring appended with a hydroxymethyl and phenoxyacetic side chain, enabling bifunctional conjugation in bioconjugate chemistry. This scaffold delivers enhanced solubility and stability under physiological conditions, facilitating efficient coupling to biomolecules via amine- or thiol-reactive derivatives.

Synthesis

  • Route1
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      77284-29-8
    • ~54%
    • In-stock
      4-(Hydroxymethyl)phenoxyacetic acid|CS-W017129
      68858-21-9

    References

    • Atherton, Eric; Logan, Christopher J.; Sheppard, Robert C. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 538 - 546
  • Route2
    • In-stock
      Sodium bicarbonate|CS-0015748
      144-55-8
    • null|null
      126771-41-3
    • ~%
    • In-stock
      4-(Hydroxymethyl)phenoxyacetic acid|CS-W017129
      68858-21-9

    References

    • US5187270 A1, ;
  • Route3
    • null|null
      103258-64-6
    • ~%
    • In-stock
      4-(Hydroxymethyl)phenoxyacetic acid|CS-W017129
      68858-21-9

    References

    • Bioorganic and Medicinal Chemistry, , vol. 16, # 23 p. 10049 - 10060

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   66.76
  • LogP   0.6423
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   4

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