2-Hydroxy-5-iodobenzonitrile

Name: 2-Hydroxy-5-iodobenzonitrile
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 685103-95-1
Cat. No. CS-0131334
Molecule weight245.02
Purity≥97%
MDL No.MFCD02683857

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 685103-95-1

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 685103-95-1
Cat. No. CS-0131334
Purity ≥97%
MDL No. MFCD02683857
Storage 4°C, protect from light, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₄INO
Molecular Weight 245.02
Synonym(s) 2-Hydroxy-5-iodo-benzonitrile
SMILES N#CC1=CC(I)=CC=C1O

Description

2-Hydroxy-5-iodobenzonitrile features a hydroxyl group ortho to a nitrile, with iodine positioned para to the hydroxyl. This arrangement enables direct functionalization in cross-coupling reactions while maintaining stability under standard conditions. The electron-withdrawing nitrile enhances reactivity at the iodinated site, facilitating efficient palladium-catalyzed transformations.

Application

2-Hydroxy-5-iodobenzonitrile serves as a versatile building block for palladium-catalyzed cross-coupling reactions, enabling efficient access to substituted phenolic scaffolds. The ortho-hydroxyl and cyano groups provide orthogonal functionality for sequential derivatization, while the iodide facilitates reliable coupling under standard conditions. Bench-stable and readily purified by recrystallization, it functions effectively in the synthesis of heterocyclic intermediates and functionalized aryl motifs relevant to medicinal chemistry and materials science.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 44.02
LogP 1.86848
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Other Classifications

Building Blocks Functional Group Phenol

Building Blocks Functional Group Cyanide/Nitrile

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

2-Hydroxy-5-iodobenzonitrile sigma2-Hydroxy-5-iodobenzonitrile manufacturer2-Hydroxy-5-iodobenzonitrile price2-Hydroxy-5-iodobenzonitrile structure2-Hydroxy-5-iodobenzonitrile SDSbuy 2-Hydroxy-5-iodobenzonitrile2-Hydroxy-5-iodobenzonitrile supplier2-Hydroxy-5-iodobenzonitrile uses2-Hydroxy-5-iodobenzonitrile molecular weightprice of 2-Hydroxy-5-iodobenzonitrile2-Hydroxy-5-iodobenzonitrile chemical name formula of 2-Hydroxy-5-iodobenzonitrile

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-Hydroxy-5-iodobenzonitrile

CAS No. 685103-95-1

Recommended Products