Lot numbers can be found on the outside label of a product:
(2-Methoxyphenyl)methanamine
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CAS No. 6850-57-3
- Cat. No. CS-W011056
- Purity≥97%
- MDL No.MFCD00008110
*For research and further manufacturing use only, not for direct human use.
Structure of 6850-57-3
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General Information
- CAS No. 6850-57-3
- Cat. No. CS-W011056
- Purity ≥97%
- MDL No. MFCD00008110
- Storage 4°C
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₈H₁₁NO
- Molecular Weight 137.18
- Synonym(s) 2-Methoxybenzylamine
- SMILES COC1=C(CN)C=CC=C1
Description
Proligos DNA phosphoramidites lead to high-yield and high-quality oligonucleotides due to their high coupling efficiency. The deprotection step of automated oligonucleotide synthesis is integral to synthesis time and final product quality. The high coupling efficiency of Proligos DNA phosphoramidites leads to high-yield and high-quality oligonucleotides.Changing the dG protecting group to the dimethylformamide (dmf) base protecting group enables the rapid synthesis of high-purity, high-yieldoligonucleotide, thus increasing the efficiency of high-throughputproduction.Key Features of dG(dmf) dG(dmf) is deprotected faster than the conventional dG(ib): thedeprotection time in concentrated ammonia is reduced to 2 hours at55 C or 1 hour at 65 CThe dG(dmf)-monomer is especially suitable for G-rich sequences:incomplete deprotection is greatly reduced in comparison with theconventional dG(ib)-monomer dG(dmf)-phosphoramidite is as stable in solution as the standard dA(bz)-,dC(bz)- and dT-phosphoramidites dG(dmf)-phosphoramidite can directly substitute for dG(ib)-phosphoramiditeNo change is required in the reagents commonly used for DNA synthesis(except a low concentration iodine oxidizer i.e., 0.02 M in iodine, should beemployed)DMT-dG(dmf) Phosphoramidite is configured for Expedite and PolyGen Synthesizers.
Synthesis
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Route1
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135-02-4 - ~62%
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In-stock
6850-57-3
References
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Ovsepyan, T. R.; Akopyan, P. R.; Safrazbekyan, R. R.; Sukasyan, R. S.; Arzanunts, E. M.; Sarkisyan, I. S.; Engoyan, A. P.; Karapetyan, A. A.; Struchkov, Yu. T. Pharmaceutical Chemistry Journal, 1998 , vol. 32, # 12 p. 641 - 643 Khimiko-Farmatsevticheskii Zhurnal, 1998 , vol. 32, # 12 p. 18 - 20
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Route2
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135-02-4
- ~87%
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In-stock
6850-57-3
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In-stock
612-16-8
References
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Organic Letters, , vol. 4, # 12 p. 2055 - 2058
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Route3
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In-stock
6609-56-9 - ~%
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In-stock
6850-57-3
References
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Journal of the American Chemical Society, , vol. 77, p. 109,112 Org. Synth. Coll., , vol. Vol. IV, p. 780,782
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Safety Information
Download SDS|
GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 2735
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501
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Quality Control
Computational Chemistry Data
- TPSA 35.25
- LogP 1.1539
- H_Acceptors 2
- H_Donors 1
- Rotatable_Bonds 2
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