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CS-W001157 4
Total: USD 88.00

3-Methylcyclohexanamine

  • CAS No. 6850-35-7

  • Cat. No. CS-D0430
  • Molecule weight113.20
  • Purity≥98%
  • MDL No.MFCD00001494

*For research and further manufacturing use only, not for direct human use.

3-Methylcyclohexanamine|CS-D0430

Structure of 6850-35-7

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General Information

  • CAS No. 6850-35-7
  • Cat. No. CS-D0430
  • Purity ≥98%
  • MDL No. MFCD00001494
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₅N
  • Molecular Weight 113.20
  • Synonym(s) 3-Methylcyclohexylamine
  • SMILES NC1CC(C)CCC1

Description

3-Methylcyclohexanamine offers a rigid, chiral amine scaffold with enhanced steric profile due to the methyl substituent. This bench-stable derivative integrates readily into asymmetric synthesis and serves as a key building block for bioactive molecule design.

Application

3-Methylcyclohexanamine serves as a versatile chiral building block in medicinal chemistry, enabling the synthesis of bioactive molecules through standard amine functionalization. Its cyclohexane scaffold provides conformational rigidity, while the tertiary amine functionality offers favorable solubility and reactivity in coupling and derivatization reactions. Bench-stable and readily purified, it functions effectively in both small-molecule drug discovery and process-scale synthesis.

Synthesis

  • Route1
    • null|null
      4701-95-5
    • ~62%
    • In-stock
      3-Methylcyclohexanamine|CS-D0430
      6850-35-7

    References

    • Pau; Cerri; Boatto; Palomba; Pintore; Filippelli; Falcone; Palagiano; Rossi Farmaco, 1997 , vol. 52, # 2 p. 93 - 98
  • Route2
    • null|null
      99-08-1
    • ~47%
    • In-stock
      3-Methylcyclohexanamine|CS-D0430
      6850-35-7
    • null|null
      109246-77-7
    • null|null
      108-44-1

    References

    • Tetrahedron Letters, , vol. 33, # 49 p. 7477 - 7480
  • Route3
    • null|null
      108-44-1
    • ~%
    • In-stock
      3-Methylcyclohexanamine|CS-D0430
      6850-35-7
    • 3-Methyl-N-(3-methylcyclohexyl)cyclohexan-1-amine, mixture of diastereomers|CS-0258085
      109496-89-1

    References

    • Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, , vol. 138, p. 1258 Annales de Chimie (Cachan, France), , vol. <8>4, p. 386

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS05
Signal Word : Danger
UN#: 2733
Class : 3,8
Packing Group : Ⅱ
Hazard Statements : H225-H314
Precautionary Statements : P210-P233-P240-P241-P242-P243-P260-P264-P280-P301+P330+P331-P304+P340-P363-P370+P378-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   1.5238
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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