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CS-W001157 4
Total: USD 88.00

5-Phenyloxazol-2-amine

  • CAS No. 6826-24-0

  • Cat. No. CS-0187169
  • Purity≥98%
  • MDL No.MFCD00087876

*For research and further manufacturing use only, not for direct human use.

5-Phenyloxazol-2-amine|CS-0187169

Structure of 6826-24-0

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General Information

  • CAS No. 6826-24-0
  • Cat. No. CS-0187169
  • Purity ≥98%
  • MDL No. MFCD00087876
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₈N₂O
  • Molecular Weight None
  • Synonym(s) 5-Phenyl-1,3-oxazol-2-amine
  • SMILES N=1C=C(OC1N)C=2C=CC=CC2

Description

5-Phenyloxazol-2-amine features a fused oxazole ring bearing a phenyl group at the 5-position and an amine at the 2-position. This configuration delivers enhanced electron density at the heterocyclic nitrogen, enabling effective coordination in catalytic systems. The compound exhibits bench-stable handling and integrates readily into functionalized scaffolds for medicinal chemistry applications.

Application

5-Phenyloxazol-2-amine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to oxazole-based scaffolds through standard coupling and functionalization reactions. Its bench-stable nature and tolerance to diverse reaction conditions facilitate straightforward incorporation into complex molecules. The amine functionality supports further derivatization via acylation, alkylation, or transition-metal-catalyzed cross-coupling, making it a practical choice for API development and library synthesis.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Computational Chemistry Data

  • TPSA   52.05
  • LogP   1.9238
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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