Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-Bromo-3-methoxynaphthalene

  • CAS No. 68251-77-4

  • Cat. No. CS-0159355
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Bromo-3-methoxynaphthalene|CS-0159355

Structure of 68251-77-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 68251-77-4
  • Cat. No. CS-0159355
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₉BrO
  • Molecular Weight 237.09
  • Synonym(s) Naphthalene,2-bromo-3-methoxy
  • SMILES COC1=C(Br)C=C2C=CC=CC2=C1

Description

2-Bromo-3-methoxynaphthalene features a bromine atom at the 2-position and a methoxy group at the 3-position of the naphthalene core, creating a uniquely activated aromatic system. This configuration enables selective coupling reactions in transition-metal-catalyzed transformations, particularly in cross-coupling protocols where controlled regiochemistry is essential. The methoxy substituent enhances solubility and stabilizes intermediates under reaction conditions.

Application

2-Bromo-3-methoxynaphthalene serves as a versatile building block in transition-metal-catalyzed cross-coupling reactions, enabling efficient construction of biaryl scaffolds. The bromine and methoxy groups offer orthogonal reactivity, facilitating sequential functionalization. Its bench-stable nature and compatibility with Pd-catalyzed protocols make it ideal for medicinal chemistry and materials synthesis workflows.

Synthesis

  • Route1
    • 2-Methoxynaphthalene Naproxen Impurity|CS-0229804
      93-04-9
    • ~90%
    • In-stock
      2-Bromo-3-methoxynaphthalene|CS-0159355
      68251-77-4

    References

    • Niimi, Kazuki; Mori, Hiroki; Miyazaki, Eigo; Osaka, Itaru; Kakizoe, Hayato; Takimiya, Kazuo; Adachi, Chihaya Chemical Communications, 2012 , vol. 48, # 47 p. 5892 - 5894
  • Route2

    References

    • Motomura, Takahisa; Nakamura, Hideko; Suginome, Michinori; Murakami, Masahiro; Ito, Yoshihiko Bulletin of the Chemical Society of Japan, 2005 , vol. 78, # 1 p. 142 - 146
  • Route3
    • null|null
      58778-69-1
    • ~%
    • In-stock
      2-Bromo-3-methoxynaphthalene|CS-0159355
      68251-77-4

    References

    • Motomura, Takahisa; Nakamura, Hideko; Suginome, Michinori; Murakami, Masahiro; Ito, Yoshihiko Bulletin of the Chemical Society of Japan, 2005 , vol. 78, # 1 p. 142 - 146

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   9.23
  • LogP   3.6109
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2-Bromo-3-methoxynaphthalene sigma2-Bromo-3-methoxynaphthalene manufacturer2-Bromo-3-methoxynaphthalene price2-Bromo-3-methoxynaphthalene structure2-Bromo-3-methoxynaphthalene SDSbuy 2-Bromo-3-methoxynaphthalene2-Bromo-3-methoxynaphthalene supplier2-Bromo-3-methoxynaphthalene uses2-Bromo-3-methoxynaphthalene molecular weightprice of 2-Bromo-3-methoxynaphthalene2-Bromo-3-methoxynaphthalene chemical name formula of 2-Bromo-3-methoxynaphthalene
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label