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CS-W001157 4
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2,4,6-Trimethoxybenzene-1,3,5-tricarbaldehyde

  • CAS No. 680575-17-1

  • Cat. No. CS-0170520
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2,4,6-Trimethoxybenzene-1,3,5-tricarbaldehyde|CS-0170520

Structure of 680575-17-1

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General Information

  • CAS No. 680575-17-1
  • Cat. No. CS-0170520
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₂O₆
  • Molecular Weight 252.22
  • Synonym(s) 2,4,6-Trimethoxy-1,3,5-benzenetricarbaldehyde
  • SMILES O=CC1=C(OC)C(C=O)=C(OC)C(C=O)=C1OC

Description

This tricarbonyl compound features three methoxy groups positioned at the 2,4,6-positions relative to a central aromatic core, delivering enhanced solubility and stability. The aldehyde functionalities enable efficient coupling in multicomponent reactions, serving as a key scaffold for macrocyclic and supramolecular architectures.

Application

2,4,6-Trimethoxybenzene-1,3,5-tricarbaldehyde serves as a versatile trifunctional building block for the synthesis of complex heterocycles and molecular scaffolds. Its three ortho-methoxy-substituted aldehyde groups enable efficient multistep condensation reactions, including Mannich-type cyclizations and Knoevenagel couplings. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis workflows in medicinal chemistry and materials science.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   78.9
  • LogP   1.1499
  • H_Acceptors   6
  • H_Donors   0
  • Rotatable_Bonds   6

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