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Structure of 67953-08-6
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Hydrolyzing γ-glutamyl bonds in enzymatic assays, L-Glutamic acid γ-(p-nitroanilide) hydrochloride (CAS 67953-08-6) serves as a chromogenic probe for γ-glutamyl transpeptidase activity detection.
L-Glutamic acid γ-(p-nitroanilide) hydrochloride (CAS 67953-08-6) inhibits SLC1A5-mediated glutamine uptake by targeting the cell membrane glutamine transporter, disrupting mitochondrial glutamine transport in esophageal adenocarcinoma cells. This blockade alters cellular redox balance. Researchers use it to probe TXNIP expression, glutathione dynamics, and ROS accumulation in human colonoid monolayers across apical and basolateral compartments.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: