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CS-W001157 4
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Methyl 5-aminopicolinate

  • CAS No. 67515-76-8

  • Cat. No. CS-W009245
  • Purity≥95%
  • MDL No.MFCD07783939

*For research and further manufacturing use only, not for direct human use.

Methyl 5-aminopicolinate|CS-W009245

Structure of 67515-76-8

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General Information

  • CAS No. 67515-76-8
  • Cat. No. CS-W009245
  • Purity ≥95%
  • MDL No. MFCD07783939
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈N₂O₂
  • Molecular Weight 152.15
  • Synonym(s) Methyl 5-aminopyridine-2-carboxylate
  • SMILES O=C(C1=NC=C(N)C=C1)OC

Description

Methyl 5-aminopicolinate features a pyridine ring bearing both methyl ester and primary amine functionalities. This dual functionality enables direct incorporation into peptide conjugation workflows or as a precursor for heterocyclic synthesis. The para-amine group enhances solubility in polar solvents and supports further derivatization under mild conditions.

Application

Methyl 5-aminopicolinate serves as a versatile building block in medicinal chemistry, enabling efficient access to nitrogen-containing heterocycles and bioactive scaffolds. The ortho-amino and ester functionalities offer complementary reactivity for selective functionalization, including coupling reactions and cyclization pathways. Its bench-stable nature and compatibility with diverse reaction conditions facilitate straightforward purification and integration into multi-step syntheses.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   65.21
  • LogP   0.4504
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

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