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CS-W001157 4
Total: USD 88.00

2,4,6-Tri-tert-butylpyrimidine

  • CAS No. 67490-21-5

  • Cat. No. CS-W012668
  • Purity≥98%
  • MDL No.MFCD03094045

*For research and further manufacturing use only, not for direct human use.

2,4,6-Tri-tert-butylpyrimidine|CS-W012668

Structure of 67490-21-5

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General Information

  • CAS No. 67490-21-5
  • Cat. No. CS-W012668
  • Purity ≥98%
  • MDL No. MFCD03094045
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₂₈N₂
  • Molecular Weight 248.41
  • Synonym(s) 2,4,6-tritert-butylpyrimidine
  • SMILES CC(C)(C)C1=CC(=NC(=N1)C(C)(C)C)C(C)(C)C

Description

2,4,6-Tri-tert-butylpyrimidine features three bulky tert-butyl groups at the 2, 4, and 6 positions of the pyrimidine ring, imparting exceptional steric shielding. This configuration enhances kinetic stability and inhibits undesired reactivity, making it a robust scaffold for sterically demanding catalytic systems and electron-rich heterocyclic architectures in synthetic methodology development.

Synthesis

  • Route1
    • null|null
      75-97-8
    • In-stock
      Trimethylacetonitrile|CS-0017904
      630-18-2
    • ~90%
    • In-stock
      2,4,6-Tri-tert-butylpyrimidine|CS-W012668
      67490-21-5

    References

    • Martinez, A. Garcia; Fernandez, A. Herrera; Jimenez, F. Moreno; Fraile, A. Garcia; Subramanian, L. R.; Hanack, M. Journal of Organic Chemistry, 1992 , vol. 57, # 5 p. 1627 - 1630
  • Route2
    • In-stock
      Trimethylacetonitrile|CS-0017904
      630-18-2
    • null|null
      917-92-0
    • ~78%
    • In-stock
      2,4,6-Tri-tert-butylpyrimidine|CS-W012668
      67490-21-5

    References

    • Martinez, A. Garcia; Fernandez, A. Herrera; Alvarez, Roberto Martinez; Losada, M. C. Silva; Vilchez, D. Molero; et al. Synthesis, 1990 , # 10 p. 881 - 882
  • Route3
    • In-stock
      Trimethylacetonitrile|CS-0017904
      630-18-2
    • null|null
      27701-32-2
    • ~45%
    • In-stock
      2,4,6-Tri-tert-butylpyrimidine|CS-W012668
      67490-21-5

    References

    • Martinez, A. Garcia; Herrera, A.; Martinez, R.; Teso, E.; Garcia, A.; et al. Journal of Heterocyclic Chemistry, 1988 , vol. 25, p. 1237 - 1241

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   25.78
  • LogP   4.3691
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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