2,5-Dichlorobenzohydrazide

Name: 2,5-Dichlorobenzohydrazide
Brand: ChemScene
Availability: InStock
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CAS No. 67487-35-8
Cat. No. CS-0220421
Purity≥98%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Description

2,5-Dichlorobenzohydrazide features a hydrazide functional group flanked by two chlorine atoms at the 2 and 5 positions of the benzene ring. This electron-deficient aromatic scaffold enables direct coupling in heterocyclic synthesis and offers enhanced stability under standard bench conditions.

Application

2,5-Dichlorobenzohydrazide serves as a versatile building block in the synthesis of heterocyclic scaffolds, particularly triazoles and imidazoles, via condensation reactions with carbonyl compounds or isothiocyanates. Its dual functional groups—hydrazide and electron-withdrawing dichloro substituents—enable high reactivity and structural diversity in medicinal chemistry campaigns. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for scalable synthesis workflows.

General Information

CAS No. 67487-35-8
Cat. No. CS-0220421
Purity ≥98%
MDL No. None
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₆Cl₂N₂O
Molecular Weight 205.04
Synonym(s) 2,5-Dichlorobenzhydrazide
SMILES ClC1=CC(C(NN)=O)=C(Cl)C=C1

Computational Chemistry Data

TPSA 55.12
LogP 1.5969
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H312-H315-H319-H332-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Functional Group Ketone

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

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2,5-Dichlorobenzohydrazide

CAS No. 67487-35-8

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