Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

5-Bromo-1H-1,2,4-triazole-3-carboxylic acid

  • CAS No. 674287-63-9

  • Cat. No. CS-0019283
  • Purity≥98%
  • MDL No.MFCD11040182

*For research and further manufacturing use only, not for direct human use.

5-Bromo-1H-1,2,4-triazole-3-carboxylic acid|CS-0019283

Structure of 674287-63-9

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 674287-63-9
  • Cat. No. CS-0019283
  • Purity ≥98%
  • MDL No. MFCD11040182
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₂BrN₃O₂
  • Molecular Weight 191.97
  • Synonym(s) None
  • SMILES O=C(C1=NN=C(Br)N1)O

Description

5-Bromo-1H-1,2,4-triazole-3-carboxylic acid features a brominated triazole core paired with a carboxylic acid group, enabling direct conjugation or derivatization. This bench-stable scaffold integrates readily into bioactive molecule design, offering enhanced electronic and steric profile for medicinal chemistry applications.

Application

5-Bromo-1H-1,2,4-triazole-3-carboxylic acid serves as a versatile building block in medicinal chemistry and heterocyclic synthesis. Its bromine substituent enables palladium-catalyzed cross-coupling reactions, while the carboxylic acid group facilitates amide formation, esterification, and metal coordination. The molecule exhibits bench stability and functional group tolerance, making it suitable for modular synthesis of triazolyl scaffolds and bioactive compounds.

Synthesis

  • Route1

    References

    • Konstantinova; Chudinov; Fateev; Matveev; Zhurilo; Shvets; Miroshnikov Russian Journal of Bioorganic Chemistry, 2013 , vol. 39, # 1 p. 53 - 71 Bioorganicheskaya Khimiya, 2013 , vol. 39, # 1 p. 61 - 80,20
  • Route2

    References

    • Konstantinova; Chudinov; Fateev; Matveev; Zhurilo; Shvets; Miroshnikov Russian Journal of Bioorganic Chemistry, 2013 , vol. 39, # 1 p. 53 - 71 Bioorganicheskaya Khimiya, 2013 , vol. 39, # 1 p. 61 - 80,20

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   78.87
  • LogP   0.2654
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 674287-63-9 sigma674287-63-9 manufacturer674287-63-9 price674287-63-9 structure674287-63-9 SDSbuy 674287-63-9674287-63-9 supplier674287-63-9 uses674287-63-9 molecular weightprice of 674287-63-9674287-63-9 chemical name formula of 674287-63-9
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label