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CS-W001157 4
Total: USD 88.00

3-Deazaadenosine

  • CAS No. 6736-58-9

  • Cat. No. CS-W014048
  • Purity≥98%
  • MDL No.MFCD00153951

*For research and further manufacturing use only, not for direct human use.

3-Deazaadenosine|CS-W014048

Structure of 6736-58-9

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General Information

  • CAS No. 6736-58-9
  • Cat. No. CS-W014048
  • Purity ≥98%
  • MDL No. MFCD00153951
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₄N₄O₄
  • Molecular Weight 266.26
  • Synonym(s) None
  • SMILES O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C3=C(C(N)=NC=C3)N=C2

Description

Inhibiting S-adenosylhomocysteine hydrolase, 3-Deazaadenosine (CAS 6736-58-9) elevates intracellular SAH levels, thereby suppressing methylation reactions and driving antiviral and immunomodulatory effects in cellular systems.

Application

3-Deazaadenosine (CAS 6736-58-9) inhibits RNA methylation to probe m6A’s role in regulating SOCS2 expression within colon cancer cells. This disruption alters key signaling pathways. Researchers leverage this to dissect IAV protein synthesis in lung epithelial lines and suppress SV40 replication in BSC40 cultures.

Safety Information

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Computational Chemistry Data

  • TPSA   126.65
  • LogP   -1.375
  • H_Acceptors   8
  • H_Donors   4
  • Rotatable_Bonds   2

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