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CS-W001157 4
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1-((2-Hydroxyethyl)thio)propan-2-ol

  • CAS No. 6713-03-7

  • Cat. No. CS-0159777
  • Molecule weight136.21
  • Purity≥97%
  • MDL No.MFCD00206294

*For research and further manufacturing use only, not for direct human use.

1-((2-Hydroxyethyl)thio)propan-2-ol|CS-0159777

Structure of 6713-03-7

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General Information

  • CAS No. 6713-03-7
  • Cat. No. CS-0159777
  • Purity ≥97%
  • MDL No. MFCD00206294
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₂O₂S
  • Molecular Weight 136.21
  • Synonym(s) Hydroxyethylthio Propanol
  • SMILES CC(O)CSCCO

Description

1-((2-Hydroxyethyl)thio)propan-2-ol features a hydroxyethylthio functional group appended to a tertiary alcohol scaffold, delivering enhanced solubility and stability in aqueous and polar organic media. This structure enables efficient incorporation into thiol-based conjugation workflows, particularly in bioconjugation and polymer modification applications where moisture tolerance and controlled reactivity are essential.

Application

1-((2-Hydroxyethyl)thio)propan-2-ol serves as a versatile bifunctional building block in synthetic chemistry, combining a thioether linkage with a tertiary alcohol and primary hydroxyl group. Its stability under standard reaction conditions enables reliable use in protecting group strategies and nucleophilic substitution cascades. The molecule facilitates efficient conjugation and functionalization in medicinal chemistry workflows, particularly in the construction of sulfonamide and thioether-containing scaffolds.

Synthesis

  • Route1
    • null|null
      60-24-2
    • null|null
      75-56-9
    • ~97%
    • In-stock
      1-((2-Hydroxyethyl)thio)propan-2-ol|CS-0159777
      6713-03-7

    References

    • Romdhani-Younes, Moufida; Chaabouni, Mohamed Moncef Journal of Sulfur Chemistry, 2012 , vol. 33, # 2 p. 223 - 228
  • Route2
    • null|null
      60-24-2
    • null|null
      127-00-4
    • ~%
    • In-stock
      1-((2-Hydroxyethyl)thio)propan-2-ol|CS-0159777
      6713-03-7

    References

    • Williams; Woodward Journal of the Chemical Society, 1948 , p. 41 Full Text Show Details Hamilton; Moggridge; Woodward Journal of the Chemical Society, 1948 , p. 47

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   0.0927
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   4

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