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CS-W001157 4
Total: USD 88.00

Nitrofurantoin

  • CAS No. 67-20-9

  • Cat. No. CS-4299
  • Purity≥98%
  • MDL No.MFCD00003224

*For research and further manufacturing use only, not for direct human use.

Nitrofurantoin|CS-4299

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General Information

  • CAS No. 67-20-9
  • Cat. No. CS-4299
  • Purity ≥98%
  • MDL No. MFCD00003224
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆N₄O₅
  • Molecular Weight 238.16
  • Synonym(s) None
  • SMILES O=C1NC(CN1/N=C/C2=CC=C([N+]([O-])=O)O2)=O

Description

Nitrofurantoin is a nitrofuran antibiotic featuring a heterocyclic core with a nitro group that enables broad-spectrum activity against uropathogenic bacteria. This compound exhibits potent bactericidal action through disruption of microbial DNA, RNA, and protein synthesis. Its rapid urinary excretion ensures high local concentrations in the bladder, making it effective for treating uncomplicated lower urinary tract infections. The molecule demonstrates stability under standard storage conditions and maintains activity across diverse bacterial strains.

Application

Nitrofurantoin serves as a clinically validated nitrofuran antibiotic, enabling targeted activity against urinary tract pathogens through intracellular reduction of its nitro group. Its structure facilitates stable storage and consistent reactivity in physiological environments, making it a reliable scaffold for antimicrobial agent studies.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS08
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H317-H334
Precautionary Statements : P261-P264-P270-P272-P280-P285-P302+P352-P330-P363-P501

Quality Control

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Computational Chemistry Data

  • TPSA   118.05
  • LogP   0.0735
  • H_Acceptors   6
  • H_Donors   1
  • Rotatable_Bonds   3

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