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Morpholine-3-carboxylic acid hydrochloride

  • CAS No. 66937-99-3

  • Cat. No. CS-0043809
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Morpholine-3-carboxylic acid hydrochloride|CS-0043809

Structure of 66937-99-3

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General Information

  • CAS No. 66937-99-3
  • Cat. No. CS-0043809
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₀ClNO₃
  • Molecular Weight 167.59
  • Synonym(s) Morpholine-3-carboxylic acid HCl
  • SMILES O=C(O)C1NCCOC1.[H]Cl

Description

Morpholine-3-carboxylic acid hydrochloride features a morpholine ring bearing a carboxylic acid group at the 3-position, delivering enhanced solubility and stability under standard conditions. This bench-stable derivative facilitates direct incorporation into peptide couplings and bioactive molecule synthesis.

Application

Morpholine-3-carboxylic acid hydrochloride serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and peptide mimetics. Its well-defined carboxylic acid functionality facilitates amide coupling, esterification, and salt formation under standard conditions. The morpholine ring provides favorable solubility and metabolic stability, while the hydrochloride salt enhances crystallinity and shelf stability, simplifying handling and purification in routine synthetic workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   58.56
  • LogP   -0.5188
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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