Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1-Methylcyclopropane-1-sulfonamide

  • CAS No. 669008-26-8

  • Cat. No. CS-W005664
  • Purity≥97%
  • MDL No.MFCD11501466

*For research and further manufacturing use only, not for direct human use.

1-Methylcyclopropane-1-sulfonamide|CS-W005664

Structure of 669008-26-8

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 669008-26-8
  • Cat. No. CS-W005664
  • Purity ≥97%
  • MDL No. MFCD11501466
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₉NO₂S
  • Molecular Weight 135.19
  • Synonym(s) 1-Methyl-cyclopropylsulfonamide
  • SMILES O=S(C1(C)CC1)(N)=O

Description

2?-Deoxyuridine 5?-monophosphate (dUMP) is used by the enzyme thymidylate synthetase (TS) (EC 2.1.1.45) for the de novo production of dTMP. dUMP is used as the reference substrate in studies of dUMP analogues in potential chemotherapy applications.

Application

1-Methylcyclopropane-1-sulfonamide serves as a stable, bench-ready sulfonamide building block with predictable reactivity in nucleophilic substitution and transition-metal-catalyzed coupling processes. Its cyclopropyl scaffold imparts rigidity and enhanced metabolic stability, making it valuable for medicinal chemistry applications. The methylated sulfonamide group offers improved solubility and functional group tolerance, facilitating efficient incorporation into complex molecular architectures.

Synthesis

  • Route1
    • Tert-butyl ((1-methylcyclopropyl)sulfonyl)carbamate|CS-0523725
      849022-29-3
    • ~91%
    • In-stock
      1-Methylcyclopropane-1-sulfonamide|CS-W005664
      669008-26-8

    References

    • BOEHRINGER INGELHEIM INTERNATIONAL GmbH; BOEHRINGER INGELHEIM PHARMA GmbH and CO KG Patent: WO2007/9227 A1, 2007 ; Location in patent: Page/Page column 43 ; WO 2007/009227 A1
  • Route2

    References

    • Hewawasam, Piyasena; Ding, Min; Sun, Li-Qiang; Scola, Paul Michael Patent: US2007/10455 A1, 2007 ; Location in patent: Page/Page column 28 ;
  • Route3
    • null|null
      923032-55-7
    • ~%
    • In-stock
      1-Methylcyclopropane-1-sulfonamide|CS-W005664
      669008-26-8

    References

    • WO2013/88256 A1, ; Page/Page column 65 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   60.16
  • LogP   -0.1726
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1-Methylcyclopropane-1-sulfonamide sigma1-Methylcyclopropane-1-sulfonamide manufacturer1-Methylcyclopropane-1-sulfonamide price1-Methylcyclopropane-1-sulfonamide structure1-Methylcyclopropane-1-sulfonamide SDSbuy 1-Methylcyclopropane-1-sulfonamide1-Methylcyclopropane-1-sulfonamide supplier1-Methylcyclopropane-1-sulfonamide uses1-Methylcyclopropane-1-sulfonamide molecular weightprice of 1-Methylcyclopropane-1-sulfonamide1-Methylcyclopropane-1-sulfonamide chemical name formula of 1-Methylcyclopropane-1-sulfonamide
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label