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Structure of 669008-26-8
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2?-Deoxyuridine 5?-monophosphate (dUMP) is used by the enzyme thymidylate synthetase (TS) (EC 2.1.1.45) for the de novo production of dTMP. dUMP is used as the reference substrate in studies of dUMP analogues in potential chemotherapy applications.
1-Methylcyclopropane-1-sulfonamide serves as a stable, bench-ready sulfonamide building block with predictable reactivity in nucleophilic substitution and transition-metal-catalyzed coupling processes. Its cyclopropyl scaffold imparts rigidity and enhanced metabolic stability, making it valuable for medicinal chemistry applications. The methylated sulfonamide group offers improved solubility and functional group tolerance, facilitating efficient incorporation into complex molecular architectures.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: