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Structure of 66739-89-7
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This boronate ester integrates a stable 1,3-dioxolan-2-yl group with a para-cyano substituent, enabling reliable Suzuki-Miyaura coupling under standard conditions. The electron-deficient aryl moiety enhances reactivity while maintaining bench-stable handling and compatibility with diverse reaction matrices.
4-(1,3-Dioxolan-2-yl)benzonitrile serves as a versatile building block in synthetic organic chemistry, enabling efficient access to functionalized aromatic systems. The 1,3-dioxolane ring acts as a stable acetal protecting group for aldehydes, which can be selectively cleaved under mild acidic conditions. This compound facilitates the introduction of aldehyde functionality at the para position of a nitrile-substituted benzene ring, supporting downstream transformations such as reductive amination, Grignard additions, or heterocycle formation. Its bench stability and compatibility with common reaction conditions make it well-suited for multi-step synthesis and process development.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 3439
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H311-H331
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501
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Lot numbers can be found on the outside label of a product: