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Structure of 66684-61-5
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1,5-Difluoro-3-methoxy-2-nitrobenzene features a uniquely activated aromatic core with orthogonal electron-withdrawing fluorine and nitro groups, enabling selective functionalization. The methoxy substituent enhances solubility while stabilizing the electronic profile. This compound serves as a high-performance building block for advanced synthetic intermediates in medicinal chemistry and agrochemical development.
1,5-Difluoro-3-methoxy-2-nitrobenzene serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient construction of substituted heterocycles via palladium-catalyzed cross-coupling reactions. The ortho-difluoro motif facilitates selective functionalization, while the methoxy and nitro groups provide orthogonal reactivity for downstream transformations. Bench-stable and compatible with standard purification methods, it functions effectively in multi-step syntheses requiring high regioselectivity and functional group tolerance.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: