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CS-W001157 4
Total: USD 88.00

2-Methoxy-5-pyridinecarboxylic acid

  • CAS No. 66572-55-2

  • Cat. No. CS-W004797
  • Purity≥98%
  • MDL No.MFCD04115721

*For research and further manufacturing use only, not for direct human use.

2-Methoxy-5-pyridinecarboxylic acid|CS-W004797

Structure of 66572-55-2

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General Information

  • CAS No. 66572-55-2
  • Cat. No. CS-W004797
  • Purity ≥98%
  • MDL No. MFCD04115721
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇NO₃
  • Molecular Weight 153.14
  • Synonym(s) 6-methoxypyridine-3-carboxylate; 6-Methoxypyridine-3-carboxylic acid
  • SMILES O=C(C1=CN=C(OC)C=C1)O

Description

2-Methoxy-5-pyridinecarboxylic acid features a pyridine ring bearing both methoxy and carboxylic acid functionalities at meta positions, enabling versatile coupling reactions. The electron-withdrawing carboxyl group enhances reactivity in amide bond formation, while the methoxy substituent improves solubility and stability under standard conditions. This compound serves as a key building block for bioactive heterocycles and pharmaceutical intermediates.

Application

2-Methoxy-5-pyridinecarboxylic acid serves as a versatile building block for pyridine-based heterocycles and pharmaceutical intermediates. Its carboxylic acid functionality enables direct amidation, esterification, or coupling reactions under standard conditions, while the methoxy group provides orthogonal reactivity and enhanced solubility. The molecule exhibits good bench stability and facilitates purification via recrystallization or column chromatography, supporting efficient integration into multi-step synthetic sequences.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   59.42
  • LogP   0.7884
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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