Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

3-Hydroxy-2-methoxybenzaldehyde

  • CAS No. 66495-88-3

  • Cat. No. CS-0071433
  • Molecule weight152.15
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-Hydroxy-2-methoxybenzaldehyde|CS-0071433

Structure of 66495-88-3

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 66495-88-3
  • Cat. No. CS-0071433
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈O₃
  • Molecular Weight 152.15
  • Synonym(s) 2-methoxy-3-hydroxybenzaldehyde
  • SMILES O=CC1=C(OC)C(O)=CC=C1

Description

3-Hydroxy-2-methoxybenzaldehyde features a strategically positioned aldehyde group flanked by hydroxyl and methoxy substituents, enabling direct integration into coupling reactions. This electron-rich scaffold supports efficient derivatization in synthetic and medicinal chemistry workflows.

Application

3-Hydroxy-2-methoxybenzaldehyde serves as a versatile ortho-hydroxy aromatic aldehyde scaffold, enabling efficient synthesis of bioactive heterocycles and natural product analogs. Its dual functionality—phenolic hydroxyl and methoxy group—provides orthogonal reactivity for selective derivatization, while the aldehyde moiety facilitates condensation reactions in Pechmann, Mannich, and Ugi-type processes. Bench-stable and readily purified by recrystallization, it functions as a reliable building block in medicinal chemistry and materials science applications.

Synthesis

  • Route1
    • In-stock
      2,3-Dihydroxybenzaldehyde|CS-W007479
      24677-78-9
    • null|null
      74-88-4
    • ~98%
    • In-stock
      3-Hydroxy-2-methoxybenzaldehyde|CS-0071433
      66495-88-3

    References

    • Boger, Dale L.; Hong, Jiyong; Hikota, Masataka; Ishida, Michio Journal of the American Chemical Society, 1999 , vol. 121, # 11 p. 2471 - 2477
  • Route2
    • null|null
      74-88-4
    • ~%
    • In-stock
      3-Hydroxy-2-methoxybenzaldehyde|CS-0071433
      66495-88-3

    References

    • Takeda Chemical Industries, Ltd. Patent: EP1591120 A1, 2005 ; Location in patent: Page/Page column 89 ; EP 1591120 A1
  • Route3

    References

    • Assens, Jean-Louis; Bernhart, Claude; Cabanel-Haudricourt, Frederique; Gautier, Patrick; Nisato, Dino Patent: US2003/225100 A1, 2003 ; Location in patent: Page 20 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   46.53
  • LogP   1.2133
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 3-Hydroxy-2-methoxybenzaldehyde sigma3-Hydroxy-2-methoxybenzaldehyde manufacturer3-Hydroxy-2-methoxybenzaldehyde price3-Hydroxy-2-methoxybenzaldehyde structure3-Hydroxy-2-methoxybenzaldehyde SDSbuy 3-Hydroxy-2-methoxybenzaldehyde3-Hydroxy-2-methoxybenzaldehyde supplier3-Hydroxy-2-methoxybenzaldehyde uses3-Hydroxy-2-methoxybenzaldehyde molecular weightprice of 3-Hydroxy-2-methoxybenzaldehyde3-Hydroxy-2-methoxybenzaldehyde chemical name formula of 3-Hydroxy-2-methoxybenzaldehyde
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label