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CS-W001157 4
Total: USD 88.00

4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-methyltetrahydrofuran-2-yl)-5-fluoropyrimidin-2(1H)-one Capecitabine Impurity

  • CAS No. 66335-38-4

  • Cat. No. CS-0213987
  • Purity≥97%
  • MDL No.MFCD07369278

*For research and further manufacturing use only, not for direct human use.

4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-methyltetrahydrofuran-2-yl)-5-fluoropyrimidin-2(1H)-one Capecitabine Impurity|CS-0213987

Structure of 66335-38-4

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General Information

  • CAS No. 66335-38-4
  • Cat. No. CS-0213987
  • Purity ≥97%
  • MDL No. MFCD07369278
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₂FN₃O₄
  • Molecular Weight 245.21
  • Synonym(s) None
  • SMILES O=C(N=C(N)C(F)=C1)N1[C@@H]2O[C@H](C)[C@@H](O)[C@H]2O

Synthesis

  • Route1

    References

    • ANGIOGENE PHARMACEUTICALS LIMITED; THE GRAY LABORATORY CANCER RESEARCH TRUST Patent: WO2006/32921 A1, 2006 ; Location in patent: Page/Page column 37-38 ;
  • Route2

    References

    • MacDonald, Peter Lindsay; Rossetto, Pierluigi; Gallina, Maurizio Patent: US2009/209754 A1, 2009 ; Location in patent: Page/Page column 9-10 ;
  • Route3
    • 5’-Deoxy-2’,3’-O-isopropylidene-5-fluorocytidine|CS-0786217
      66335-37-3
    • ~86%
    • In-stock
      4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-methyltetrahydrofuran-2-yl)-5-fluoropyrimidin-2(1H)-one Capecitabine Impurity|CS-0213987
      66335-38-4

    References

    • Procopio, Antonio; Gaspari, Marco; Nardi, Monica; Oliverio, Manuela; Romeo, Roberto Tetrahedron Letters, 2008 , vol. 49, # 12 p. 1961 - 1964

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   110.6
  • LogP   -1.3963
  • H_Acceptors   7
  • H_Donors   3
  • Rotatable_Bonds   1

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