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CS-W001157 4
Total: USD 88.00

Methyl 3-amino-4-(methylamino)benzoate

  • CAS No. 66315-16-0

  • Cat. No. CS-0029666
  • Purity≥98%
  • MDL No.MFCD12922710
  • HazMat Fee +

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    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Methyl 3-amino-4-(methylamino)benzoate|CS-0029666

Structure of 66315-16-0

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Description

Methyl 3-amino-4-(methylamino)benzoate features a dual amine handle—primary amino and N-methylamino—positioned ortho to the ester group, enabling selective derivatization. This arrangement supports efficient coupling reactions in peptide synthesis and bioconjugation workflows. The molecule exhibits enhanced solubility in polar organic solvents and stability under standard bench conditions.

Application

Methyl 3-amino-4-(methylamino)benzoate serves as a versatile building block in medicinal chemistry, enabling the synthesis of substituted benzimidazoles and other heterocyclic scaffolds via condensation and cyclization reactions. The ortho-amino and methylamino groups provide complementary reactivity for sequential functionalization, while the ester moiety allows for controlled derivatization. Bench-stable and readily purified by crystallization, it facilitates efficient access to complex molecular architectures in API development workflows.

General Information

  • CAS No. 66315-16-0
  • Cat. No. CS-0029666
  • Purity ≥98%
  • MDL No. MFCD12922710
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₂N₂O₂
  • Molecular Weight 180.20
  • Synonym(s) Methyl 3-amino-4-(methylamino)benzenecarboxylate
  • SMILES O=C(OC)C1=CC=C(NC)C(N)=C1

Computational Chemistry Data

  • TPSA   64.35
  • LogP   1.0971
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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