Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

trans-4-(Hydroxymethyl)cyclohexanecarboxylic acid

  • CAS No. 66185-74-8

  • Cat. No. CS-W001267
  • Purity≥97%
  • MDL No.MFCD10566907

*For research and further manufacturing use only, not for direct human use.

trans-4-(Hydroxymethyl)cyclohexanecarboxylic acid|CS-W001267

Structure of 66185-74-8

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 66185-74-8
  • Cat. No. CS-W001267
  • Purity ≥97%
  • MDL No. MFCD10566907
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₄O₃
  • Molecular Weight 158.20
  • Synonym(s) None
  • SMILES OC[C@H]1CC[C@@H](CC1)C(O)=O

Description

trans-4-(Hydroxymethyl)cyclohexanecarboxylic acid features a rigid cyclohexane scaffold with a hydroxymethyl group and carboxylic acid moiety in trans configuration, enabling precise stereochemical control in synthetic routes. This bench-stable derivative serves as a valuable chiral building block for medicinal chemistry and natural product synthesis.

Application

trans-4-(Hydroxymethyl)cyclohexanecarboxylic acid serves as a versatile chiral building block in medicinal chemistry, enabling the synthesis of bioactive molecules through established functional group transformations. Its cyclohexane scaffold offers conformational rigidity, while the pendant hydroxymethyl and carboxylic acid groups provide orthogonal reactivity for derivatization, esterification, or coupling reactions. The compound exhibits excellent bench stability and facilitates purification via standard techniques, supporting scalable synthesis workflows in API development.

Synthesis

  • Route1
    • cis-4-methylcyclohexane-1-carboxylic acid|CS-0114192
      934-67-8
    • ~%
    • In-stock
      trans-4-(Hydroxymethyl)cyclohexanecarboxylic acid|CS-W001267
      66185-74-8

    References

    • Chemistry - A European Journal, , vol. 18, # 52 p. 16677 - 16688

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   57.53
  • LogP   0.8697
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 66185-74-8 sigma66185-74-8 manufacturer66185-74-8 price66185-74-8 structure66185-74-8 SDSbuy 66185-74-866185-74-8 supplier66185-74-8 uses66185-74-8 molecular weightprice of 66185-74-866185-74-8 chemical name formula of 66185-74-8
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label