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CS-W001157 4
Total: USD 88.00

Nimodipine API

  • CAS No. 66085-59-4

  • Cat. No. CS-0168328
  • Molecule weight418.44
  • Purity≥98%
  • MDL No.MFCD00153848

*For research and further manufacturing use only, not for direct human use.

Nimodipine API|CS-0168328

Structure of 66085-59-4

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General Information

  • CAS No. 66085-59-4
  • Cat. No. CS-0168328
  • Purity ≥98%
  • MDL No. MFCD00153848
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₁H₂₆N₂O₇
  • Molecular Weight 418.44
  • Synonym(s) Nimodipine
  • SMILES O=C(C1=C(C)NC(C)=C(C1C2=CC([N+]([O-])=O)=CC=C2)C(OC(C)C)=O)OCCOC

Synthesis

  • Route1
    • Isopropyl (Z)-3-aminobut-2-enoate|CS-1720173
      40100-28-5
    • In-stock
      2-Methoxyethyl 2-(3-Nitrobenzylidene)-3-oxobutyrate|CS-0155156
      39562-22-6
    • ~80%
    • In-stock
      Nimodipine API|CS-0168328
      66085-59-4

    References

    • Meyer; Wehinger; Bossert; Scherling Arzneimittel-Forschung/Drug Research, 1983 , vol. 33, # 1 p. 106 - 112
  • Route2

    References

    • Arzneimittel-Forschung/Drug Research, , vol. 33, # 1 p. 106 - 112
  • Route3
    • In-stock
      2-Methoxyethyl 3-oxobutanoate|CS-W016168
      22502-03-0
    • 3-Nitrobenzaldehyde Erlotinib Impurity|CS-0204123
      99-61-6
    • null|null
      143093-33-8
    • ~70%
    • In-stock
      Nimodipine API|CS-0168328
      66085-59-4
    • Diisopropyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate Nimodipine Impurity|CS-0532882
      21881-78-7

    References

    • Yiu, Sai-Hay; Knaus, Edward E. Archiv der Pharmazie, 1997 , vol. 330, # 1-2 p. 35 - 43

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   117
  • LogP   2.9708
  • H_Acceptors   8
  • H_Donors   1
  • Rotatable_Bonds   8

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