2-Chloro-6-fluorobenzamide

Name: 2-Chloro-6-fluorobenzamide
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 66073-54-9
Cat. No. CS-0150060
Purity≥98%
MDL No.MFCD00055436

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 66073-54-9

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 66073-54-9
Cat. No. CS-0150060
Purity ≥98%
MDL No. MFCD00055436
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₅ClFNO
Molecular Weight 173.57
Synonym(s) 2-Fluoro-6-chlorobenzamide
SMILES FC1=CC=CC(Cl)=C1C(N)=O

Description

2-Chloro-6-fluorobenzamide features a strategically positioned chloro and fluoro substituent on the benzene ring, delivering enhanced electron-withdrawing character and metabolic stability. This combination improves binding affinity in target-directed synthesis and provides robust performance under standard reaction conditions.

Application

2-Chloro-6-fluorobenzamide serves as a versatile building block in medicinal chemistry, enabling direct incorporation of ortho-halogenated aromatic scaffolds into target molecules. Its dual halogen functionality supports palladium-catalyzed cross-coupling reactions, while the amide group provides stability and polarity advantageous for purification. The compound exhibits excellent bench stability and compatibility with standard synthetic workflows.

Synthesis

Route1
- In-stock
  
  668-45-1
- ~79%
- In-stock
  
  66073-54-9
References
- Balicki, Roman; Sobotka, Wieslaw; Ejmocki, Zdzislaw Polish Journal of Chemistry, 1991 , vol. 65, # 5-6 p. 1049 - 1053
Route2
- 443-33-4
- ~83%
- In-stock
  
  66073-54-9
References
- Garcia-Alvarez, Rocio; Diaz-Alvarez, Alba E.; Borge, Javier; Crochet, Pascale; Cadierno, Victorio Organometallics, 2012 , vol. 31, # 17 p. 6482 - 6490
Route3
- 79455-63-3
- ~%
- In-stock
  
  66073-54-9
References
- Bioorganic and Medicinal Chemistry Letters, , vol. 20, # 3 p. 1128 - 1133

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352-P304+P340

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 43.09
LogP 1.578
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Functional Group Amide

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

2-Chloro-6-fluorobenzamide sigma2-Chloro-6-fluorobenzamide manufacturer2-Chloro-6-fluorobenzamide price2-Chloro-6-fluorobenzamide structure2-Chloro-6-fluorobenzamide SDSbuy 2-Chloro-6-fluorobenzamide2-Chloro-6-fluorobenzamide supplier2-Chloro-6-fluorobenzamide uses2-Chloro-6-fluorobenzamide molecular weightprice of 2-Chloro-6-fluorobenzamide2-Chloro-6-fluorobenzamide chemical name formula of 2-Chloro-6-fluorobenzamide

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-Chloro-6-fluorobenzamide

CAS No. 66073-54-9

Recommended Products

General Information

Description

Application

Synthesis

References

References

References

Safety Information

Quality Control

Computational Chemistry Data

Similar Products

Other Classifications

Recently Viewed Products

Key Words