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Structure of 660406-84-8
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tert-Butyl 4-(2-cyanoacetyl)piperidine-1-carboxylate features a piperidine core functionalized with a cyanoacetyl group, enabling direct incorporation into heterocyclic scaffolds. The tert-butyl ester provides stability and ease of removal under mild acidic conditions, while the nitrile moiety serves as a key handle for downstream transformations such as Michael additions or cyclizations. This compound delivers a robust, moisture-tolerant platform for constructing complex nitrogen-containing architectures in medicinal chemistry and synthetic methodology development.
tert-Butyl 4-(2-cyanoacetyl)piperidine-1-carboxylate serves as a versatile building block for heterocyclic synthesis, enabling efficient access to substituted piperidine scaffolds. The molecule combines a readily hydrolyzable tert-butyl ester with a reactive cyanoacetate moiety, facilitating transformations such as Michael additions, cyclizations, and subsequent functionalization. Its bench-stable nature and compatibility with standard purification protocols make it well-suited for iterative synthetic campaigns in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: