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Methyl 5-methoxy-2,3-dihydro-1H-indene-2-carboxylate

  • CAS No. 65844-46-4

  • Cat. No. CS-0322707
  • Molecule weight206.24
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Methyl 5-methoxy-2,3-dihydro-1H-indene-2-carboxylate|CS-0322707

Structure of 65844-46-4

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General Information

  • CAS No. 65844-46-4
  • Cat. No. CS-0322707
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₄O₃
  • Molecular Weight 206.24
  • Synonym(s) methyl 5-methoxyindane-2-carboxylate
  • SMILES COC1=CC=C2CC(CC2=C1)C(=O)OC

Synthesis

  • Route1
    • Methyl 6-methoxy-1-oxo-2,3-dihydro-1h-indene-2-carboxylate|CS-0215326
      22955-78-8
    • null|null
      64-19-7
    • ~63%
    • Methyl 5-methoxy-2,3-dihydro-1H-indene-2-carboxylate|CS-0322707
      65844-46-4

    References

    • ELI LILLY AND COMPANY Patent: WO2004/80968 A1, 2004 ; Location in patent: Page 58 ; WO 2004/080968 A1
  • Route2
    • Methyl 6-methoxy-1-oxo-2,3-dihydro-1h-indene-2-carboxylate|CS-0215326
      22955-78-8
    • ~31%
    • Methyl 5-methoxy-2,3-dihydro-1H-indene-2-carboxylate|CS-0322707
      65844-46-4

    References

    • BOGER, Dale L. Patent: WO2012/106569 A1, 2012 ; Location in patent: Page/Page column 102 ; WO 2012/106569 A1
  • Route3
    • null|null
      58461-21-5
    • ~45%
    • Methyl 5-methoxy-2,3-dihydro-1H-indene-2-carboxylate|CS-0322707
      65844-46-4

    References

    • METABOLEX, INC.; SHI, Dong Fang; SONG, Jiangao; MA, Jingyuan; NOVACK, Aaron; PHAM, Phuongly; NASHASHIBI, Imad; RABBAT, Christopher J.; CHEN, Xin Patent: WO2011/159297 A1, 2011 ; Location in patent: Page/Page column 134-135 ; WO 2011/159297 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   35.53
  • LogP   1.583
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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